Berberine is a golden yellow alkaloid obtained from the roots and stems of Berbaris aristata or more commonly known as barberry. Berberine is also found in other plant like Hydratis candensis (Goldenseal), coptis chinensis (Coptis or Golden thread), Berberis aquifolium (Oregon grape). These berberine containing plants are used medicinally in virtually all traditional medical systems and have a history of usage in ayurvedic and chinese medicine dating back atleast 3000 years.
The roots of Coptis or Golden thread are regarded as tonic and is used as cholagogue, stomachic, laxative, diaphoretic, antipyretic and antiseptic. Additionally, it is used externally for ocular ailments, indolent ulcers and in hemorrhoids.
- Botanis Source: Berbaris aristata/ Coptis chinensis
- Part of Used: Root & Bark
- Appearance: Yellow fine powder
Berberine HCL from RDHealthIngredients
|Berberine HCL ≥ 97%, EP/ USP/ GB||Botanis Source: Berbaris aristata/ Coptis chinensis|
Part of Used: Root & Bark
Solvent Used: Water & Ethanol
Appearance: Yellow Fine Powder
Food , Pahramceutical Grade, Kosher, Halal
|Berberine HCL Granular ≥ 85%||Botanis Source: Berbaris aristata/ Coptis chinensis|
Part of Used: Root & Bark
Appearance: Yellow granular
≥90% between 30-120mesh
|Applications: Berberine HCL can be widely applied in Dietary Supplements, Herbal blends, Tablets/Capsules.|
|Storage and Package: Keep in cool and dry place of room temperature, out of direct light and heat; in 25kg/drum, plastic bag inside, or 1kg/aluminum foil bag;|
Shelf life: 24 months within proper storage.
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Over and above all, berberine improves the host defence by immunostimulating effects and improving the blood flow to the spleen, and by activating the macrophages. Due to its antiinfective activity, berberine, finds use in dental care and urinary tract infections .
Berberine and its hydrochloride / sulphate salts are considered nontoxic in clinical doses. It is safe with no genotoxicity, cytotoxicity or mutagenicity. The therapeutic dose of berberine salts for oral supplementation is 200 mg two to four times daily
- Anonymous. The Wealth of India Vol 2B, 114-116, 1988
- Rabbani GH et al, Randomized controlled trail of berberinesulphate therapy for diarrhea due to enterotoxigenic Escherichia coli and Vibrio cholerae J. Infect . Dis 155, 979- 984 ,1987
- Vennerstorm JL et al, Berberine derivatives as antileishmanial drugs. Antimicrob Agents Chemother 34, 918-21, 1990.
- Phillipsm JD, Wright CW. Medicinal plants in tropical medicine: I Medicinal plants against protozoal diseases Trans R. Soc Trop Med Hyg 85, 18-21, 1991
- Birdsall TC, Kelly GS. Berberine: Therapeutic potential of an alkaloid found in several medicinal plants. Alt Med Rev 2(2), 94-103, 1997
- Mohan M et al, Beberine in trachoma Ind J Opthalmol, 30, 69- 75, 1982
- Khosla PK et al, Berberine, a potential drug for trachoma. Rev Int Trach Pathol Ocl Trop Subtrop Sante Publique 69, 147- 165,1992